Throughout history, indigenous cultures have harnessed the transformative and healing powers of Sacred Medicines. Whether for physical, emotional, or spiritual ailments, these natural tools have guided countless individuals toward healing, connection, and enlightenment.
At our Arkana Spiritual Retreat Centers, we work with ancestral medicines including:
Each medicine carries profound wisdom and power, guiding seekers toward inner peace, spiritual awakening, and healing.
Ayahuasca, often called the "Vine of the Soul", is a sacred tea brewed from the Banisteriopsis caapi vine and Chacruna leaves (Psychotria viridis). Used for centuries by Amazonian shamans, this plant medicine facilitates deep physical, emotional, and spiritual healing.
During an Ayahuasca ceremony, experienced shamans guide participants with sacred icaros (healing songs) and tools like Mapacho (Amazonian tobacco) to create a safe, transformative space. The experience may involve:
Ayahuasca purifies the body, realigns the spirit, and provides profound emotional and spiritual release, guiding participants toward clarity, healing, and enlightenment.
Ayahuasca is known to help treat:
San Pedro, or Huachuma, is a sacred cactus native to the Andes Mountains. It contains mescaline, a heart-opening alkaloid that fosters emotional clarity, peace, and deep connection to nature.
San Pedro ceremonies are grounding and heart-opening, often described as being “held in the embrace of an ethereal goddess.” Participants experience:
San Pedro facilitates grounding energy, emotional healing, and reconnection with life’s beauty, making it ideal for seekers of peace and harmony.
Unlike Peyote, Wachuma is often described as gentle and maternal, offering:
This powerful medicine comes from the Sonoran Desert Toad (Bufo Alvarius), which secretes 5-MeO-DMT in its parotid glands—a highly potent psychoactive compound. Often called "The God Molecule," it is renowned for its ability to induce mystical, ego-dissolving, and non-dual states of consciousness. Many who experience it describe direct encounters with the divine, universal oneness, or pure consciousness, akin to Hindu Moksha and Samadhi or Buddhist Nirvana. Every year, during the rainy season, this animal comes out of its hybernation and this is when the medicine is harvested.
Please note: The animal is not harmed during this process, after collection, it is released back to its habitat.
Participants inhale this medicine in the form of a vapor and within seconds will feel the effects. This short and intense experience usually lasts anywhere from 10 minutes to an hour. Most participants report:
Sapo offers profound and transformative healing:
Peyote is a small, sacred cactus containing mescaline. Indigenous tribes in North America have used it ceremonially for millennia to foster spiritual connection and insight. In Mexico, it is used by the Wixárika (Huichol) tribe, who call it Hikuri, or the Blue Deer. For them, it is a sacrament that allows them to connect to their ancestors and to the forces of mother nature.
In the Huichol tradition, the Hikuri ceremonies are led by their spiritual guides known as the Mara'akáme, which translates to "those that know". Their role is integral to the community and they're seen as the link between the earthly world and the spirit world. As a part of the ritual, participants gather around the sacred fire (Tatewari), they consume the peyote buttons, and sit in contemplation, as the Marakame chants all night to open interdimensional portals called nierikas to invoke the blessings and healing of the medicine.
Participants often experience visions, insights, and deep introspection, guided by ceremonial prayers and rituals. Peyote connects seekers to their ancestral wisdom and spiritual truth.
What are Niños Santos (Holy Children) ?
Niños Santos (Holy Children), is the name given to Psilocybin Mushrooms by the Mazatec Indigenous Group in the highlands of Oaxaca in Mexico. Sought after for their ability to induce altered states of consciousness and their profound healing properties, these powerful entheogens have been used for thousands of years in Mexico. As a part of the Psychedelic Renaissance of recent years, Psilocybin is a compound that has been at the forefront of scientific research for their therapeutic use. Universities such as John Hopkins and the Imperial College of London have conducted research studies evaluating their effectiveness in treating conditions like depression, social anxiety, PTSD, and addiction. Positive results from these studies are paving the way for their legalization as a natural alternative to help combat the mental health crisis in the modern world.
In the Mazatec culture, Niños Santos are used as a means to connect spiritually with the divine creating a space of healing. They are used in a ritual called a Velada (Vigil), a sacred nighttime ceremony led by a Medicine Guide. The velada is not for recreation but for deep healing, seeking wisdom, and connecting with the sacred. Participants may experience visions, receive messages from ancestors, or undergo emotional purging. As a part of this ritual, the guide will elevate prayers to the Niños Santos in the form of sacred medicine songs that evoke the feeling of gentle lullabies.
From Ayahuasca and San Pedro to Bufo and Peyote, these Sacred Medicines offer profound healing opportunities. When approached with respect, intention, and skilled guidance, they serve as portals to physical, emotional, and spiritual transformation.
Whether you seek to heal trauma, release limiting beliefs, or reconnect with universal truth, ancestral medicines hold the wisdom and power to guide you toward your highest self.
Ayahuasca is a sacred plant medicine traditionally used by Indigenous Amazonian cultures for spiritual healing and insight. At Arkana, we honor this ancient wisdom by offering ceremonies led by experienced Master Shamans in a safe, intentional setting.
Ayahuasca is made from two plants: the Ayahuasca vine (Banisteriopsis caapi) and the leaves of the Chacruna plant (Psychotria viridis), which together activate a visionary state. This allows you to journey deep within your consciousness, where healing, emotional release, and spiritual clarity can emerge.
More than a psychedelic, Ayahuasca is a teacher — what many call "the Vine of the Soul" — guiding you toward profound transformation, always with deep respect and intention.
An Ayahuasca ceremony is a sacred event held in the evening, guided by our Master Shamans through traditional icaros (healing songs), rituals, and protective spiritual practices. You'll be lying down in a quiet, candle-lit space — often in a maloka — as the medicine guides your inner journey.
You may experience visions, emotional purging, memories, or a sense of profound connection with nature and spirit. While each journey is unique, many describe it as one of the most meaningful experiences of their lives.
At Arkana, we prepare you gently and support you throughout. You are never alone. We hold space for your healing with reverence, love, and expertise.
Yes — when used in a supportive, properly guided setting like Arkana's retreats, Ayahuasca is considered safe for most people. We take your wellbeing seriously. Each guest is carefully screened in advance, and our experienced team, including medical professionals, is present throughout your stay.
Ayahuasca can bring intense emotional and physical release, which is part of the healing process. Our approach ensures you're never alone — you're supported, cared for, and held in a sacred space that prioritizes both your spiritual and physical safety.
For more, visit our Health and Safety page.
When held in a professionally guided and loving ceremonial space like Arkana's, psilocybin has shown great promise in supporting mental health. Scientific studies and spiritual traditions alike recognize its potential for helping with depression, anxiety, trauma, and emotional stagnation.
That said, we take each person's health seriously. Before joining us, you'll go through a personal screening to ensure psilocybin is appropriate for your journey. Healing is never rushed — it unfolds gently, with respect for your story and spirit.
Psilocybin Mushrooms, often called "magic mushrooms," are natural fungi that contain psilocybin, a compound known to induce expanded states of consciousness. At Arkana, we honor this sacred medicine as a tool for deep emotional healing, clarity, and spiritual awakening.
Used ceremonially for thousands of years by Indigenous cultures, psilocybin can gently open the heart and quiet the mind. It is especially helpful for releasing emotional blockages, rediscovering joy, and reconnecting with your true self — all in a safe and nurturing environment.
The effects of a psilocybin journey typically last between 4 to 6 hours. During this time, you may experience heightened sensory awareness, vivid imagery, emotional release, or a sense of unity with nature and the universe.
At Arkana, we guide you through this journey with the utmost care. The experience unfolds in a ceremonial setting, where our facilitators hold space for your healing while helping you stay grounded, safe, and supported throughout the process.
Bufo Alvarius, also known as the "Toad Medicine," is a sacred secretion from the Sonoran Desert toad that contains 5-MeO-DMT — one of the most powerful entheogens known to humanity. Unlike other plant medicines, Bufo can dissolve the ego entirely in moments, often leading to a sense of oneness with all that is.
At Arkana, we approach this medicine with the deepest reverence. It is offered only in specific ceremonies for those who are ready. The experience is short — 15 to 30 minutes — but the insights can be life-changing. This is not recreational; it is sacred.
Many describe the Bufo experience as a "rebirth" — a moment of complete surrender, followed by peace, clarity, and profound love. Some feel like they dissolve into light or enter a space beyond time. Others experience intense emotional release followed by stillness.
Our facilitators guide each Bufo ceremony with utmost care, always checking readiness, setting sacred space, and ensuring safety. You are never alone — even in the most expansive moments, you are held in a field of compassion and grounded support.
Because of its intensity, Bufo should only be taken in ceremonial settings with experienced facilitators — which is exactly what we provide at Arkana. We carefully assess each guest's physical and emotional readiness before offering this medicine.
We never pressure participation. Bufo is available only as an optional add-on for those who feel called. Our commitment is to your wellbeing — every step is intentional, respectful, and grounded in sacred tradition.
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Peyote use is legal within specific spiritual and ceremonial contexts under protections for Indigenous practices. At Arkana, we honor this medicine by working in alignment with traditional wisdom-keepers and by holding ceremonies in ethical, culturally respectful ways.
We recognize that Peyote is not just a plant — it is a sacred teacher. We are committed to stewardship, conservation, and right relationship with the cultures who have long held its wisdom. Gratitude and respect guide every step.
A Peyote ceremony is often experienced as gentle and heart-centered. You may feel more present in your body, more connected to nature, or moved by deep emotional insights. The journey typically lasts 8 to 12 hours and often includes singing, drumming, and storytelling.
It is not about "tripping" — it's about remembering. Remembering your truth, your path, your connection to all that is. And with Arkana, you walk that path in community, supported by caring guides and held by ancient wisdom.
Peyote is a small cactus native to North America, containing mescaline — a natural psychedelic revered by Indigenous cultures for centuries. It is considered a "heart-opening" medicine that fosters deep spiritual connection, inner wisdom, and gratitude for life.
At Arkana, Peyote ceremonies are held with profound respect, guided by Indigenous traditions that center prayer, music, and communal intention. The experience unfolds over many hours, creating space for reflection, healing, and reconnection with the sacred.